Research Area in Bioinformatics

Immagine
Bioinfo

The research activities of the Research Area have contributed to the discovery and characterization of different markers of tumor progression especially in brain tumors such as the description of the mechanism of action of one of the most recurrent translocations of human tumors, the FGFR3-TACC3 fusion. The group also contributed to the discovery and definition of the molecular subtypes of gliomas within the international network of TCGA researchers (The Cancer Genome Atlas).

Research lines:

  • Computational and statistical methods to analyze and reconstruct biological networks
  • Computational and statistical methods to analyze and reconstruct cancer evolution, cancer molecular subtypes, cancer biomarkers, and cancer genome alterations.
  • Computational and statistical methods to analyze and annotate genomics data.
  • Statistical Modeling and Analysis of Omic-data. Functional analysis.

 

  • Irving Cancer Center (Prof. Pierre Baldi),
  • Columbia University, NYC, USA (Prof. Antonio Iavarone);
  • Henry Ford Hospital, Detroit, USA;
  • Hôpital de la Pitié-Salpêtrière, Paris;
  • University Health Network, Toronto;
  • Qatar Computing Research Institute;
  • Stazione Zoologica A. Dohrn.